Previously, I had blogged my opinion on the protein Laminin and its supposedly “cross” shape. The shape of this protein was seized upon by one evangelist, Louie Giglio to support a proposition in his sermon. I did not know much about the protein at that time (except what I wrote in that blog) and I was reluctant to believe that a scientist would say that the protein was “cross” shaped partly due to the sensationalism of Louie, I must admit. 
However, I now have found some interesting information regarding this protein’s role in cancer research.
Recently, whilst I was reading the [excellent introductory pathology and core text in my course] book, Cell, Tissue and Disease by Prof. Neville Woolf (2000), I came across this little paragraph about laminin:
“Laminin is a cross-shaped glycoprotein present in both the basement membrane and the interstitial stroma. In normal cells laminin receptors occur on the aspect of the cell apposed to the basement membrane and are occupied by basement membrane laminin. Invasive cells, however, have laminin receptors diffusely distributed over the entire cell surface and these are often unoccupied. If such tumour cells are treated with the receptor binding fragment of laminin, their invasiveness is greately reduced” [my emphases]
Firstly, the author refers to this protein explicitly as “cross-shaped”, so Louie’s description was accurate. Secondly, it appears Laminin fragments reduce the metastatic potential of a neoplastic (tumorous) growth and hence, rids the neoplasm of its dangerous property. This potential therapy can be used if the cancerous growth had not metastasized already. Even if the cancer has spread, it could (in theory) arrest further spreading. It should be noted that this is less likely to happen naturally even when there is enough laminin in the body [to arrest the spreading of a cancer] because there is little laminin fragments freely floating around in the body. I suspect that the laminin fragments have therapeutic potential because they don’t have the binding domain for the basement membrane, otherwise (I think) they might actually help the invasive cell to adhere to the basement membrane and achieve malignancy easily!
So, the cross shaped Laminin not only proves God’s promises to be true, it helps scientists to cure cancer! 
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